Monday, April 13, 2020

Mapping Period in Cancer Treatment



Genetic Mapping Period in Cancer Treatment



Cancer, one of the most important health problems of our age, can now be successfully treated with positive developments in recent years. General approaches in the treatment of cancer, which has started to cease to be a “fearful disease”, are replaced by “cancer cell oriented” personalized practices. The inside of the cancer cell is displayed by removing the "genetic mapping of the cancer" and the damage to the cell is detected. Drug treatment, which is applied exclusively to the diseased cancer cell according to the extent of the damage, allows the person to overcome the disease without damaging their healthy cells.

Cells that grow uncontrollably cause cancer

Billions of cells in the body take shape according to the organ. The functions of liver, lung, stomach and spleen cells are specific to that organ. The transmission systems inside the cells send various signals from the surface of the cell to the nucleus. The regular and coordinated functioning of these signal pathways and the cell nucleus is important for life to continue. If a break occurs, unnecessary signals are transmitted to the cell nucleus. This causes cells to divide and multiply uncontrollably. Uncontrolled growth disrupts the function of normal cells, causing cancer to enter human life.

Aggressive cancer appears fast

Cancer is one of the most important health problems of today. The factors that cause cancer are primarily; smoking, malnutrition, overweight, sedentary life and stressful lifestyle are listed. These risk factors must cause a number of genetic changes in the cells to cause cancer. As soon as these harmful genetic changes cannot be renewed by the defense system of the human body, the cancer process begins. Cancer is not a momentary event or a sudden disease. Some cancers develop over the months, some cancers develop over the years, creating a life-threatening risk. This is associated with the “aggressiveness” of cancer. If the cancer is of an aggressive nature, it occurs within months, if not an aggressive cancer, it occurs over the years.


Cancer type and patient-specific treatment

“Cancer treatment is determined according to the stage. The disease diagnosed in the early stages can be treated by surgical method. In cancer types diagnosed in advanced stages, chemotherapy and radiotherapy are included in the treatment. Chemotherapy is actually called systemic therapy. That means treatment that concerns the whole body. In systemic treatment, besides chemotherapy, there are smart drugs and immunotherapy. Drug treatment in cancer is determined according to the type of disease, stage, patient's age, general condition, additional diseases, tumor character, degree of aggressiveness of the tumor. If drug treatment is to be applied, it should be decided whether to do this before or after surgery. While these treatment steps are on the agenda in the early stages, drug therapy is frequently used in the advanced stages.

With a simple blood test, the damage caused by cancer to the cell can be detected.

Cancer, which was one of the most feared diseases of the time, is gradually moving away from being a disease to be feared with personalized treatment. New advances in treatment continue day by day, and cell-specific therapies that cause cancer come to the fore. In the new generation treatment method that creates the genetic map of the cancer cell, the inside of the cancer cell can be seen more clearly. Cancer tissue examination or blood test is performed with this method called “Next Generation Sequencing” NGS (Next Generation Sequencing). With the researches carried out on the cancerous cell, the damage to be occurred on 600 roads, which prepares the ground for the proliferation of cells, up to 600 genes, is determined and drug treatment is applied to repair the disruption at these points.

The effect of immunotherapy is also measured

As a result of NGS examination, patients are sometimes treated with pills and sometimes with various serum treatments. This review also reveals how far immunotherapy can be cultivated. In the test, the emergence of cancer at an advanced stage can give the good news that immunotherapy will give positive results and the person can overcome the disease.

Reduces side effects of drugs


It is planned that the treatment will take place in this direction by mapping the cancer in the NGS method, which determines which point is damaged, which point needs repair, by mapping the cancer, which enables the start of a new period in cancer treatment. Genetic examination of the disease is performed with cell or blood samples taken from a patient with breast cancer. As a result of this examination, it is determined in which way the cancer occurs due to the disorder and how much damage the cell has caused. Then, the drug that will repair the disorder is determined and a treatment plan is made accordingly. Thus, the way to the patient's health is opened by using both more effective treatment and drugs with less side effects.


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