Genetic Mapping Period in Cancer Treatment
Cancer, one of the most important health problems of our
age, can now be successfully treated with positive developments in recent
years. General approaches in the treatment of cancer, which has started to
cease to be a “fearful disease”, are replaced by “cancer cell oriented”
personalized practices. The inside of the cancer cell is displayed by removing
the "genetic mapping of the cancer" and the damage to the cell is
detected. Drug treatment, which is applied exclusively to the diseased cancer
cell according to the extent of the damage, allows the person to overcome the
disease without damaging their healthy cells.
Cells that grow uncontrollably cause cancer
Billions of cells in the body take shape according to the
organ. The functions of liver, lung, stomach and spleen cells are specific to
that organ. The transmission systems inside the cells send various signals from
the surface of the cell to the nucleus. The regular and coordinated functioning
of these signal pathways and the cell nucleus is important for life to
continue. If a break occurs, unnecessary signals are transmitted to the cell
nucleus. This causes cells to divide and multiply uncontrollably. Uncontrolled
growth disrupts the function of normal cells, causing cancer to enter human
life.
Aggressive cancer appears fast
Cancer is one of the most important health problems of
today. The factors that cause cancer are primarily; smoking, malnutrition,
overweight, sedentary life and stressful lifestyle are listed. These risk
factors must cause a number of genetic changes in the cells to cause cancer. As
soon as these harmful genetic changes cannot be renewed by the defense system
of the human body, the cancer process begins. Cancer is not a momentary event
or a sudden disease. Some cancers develop over the months, some cancers develop
over the years, creating a life-threatening risk. This is associated with the
“aggressiveness” of cancer. If the cancer is of an aggressive nature, it occurs
within months, if not an aggressive cancer, it occurs over the years.
Cancer type and patient-specific treatment
“Cancer treatment is determined according to the stage. The
disease diagnosed in the early stages can be treated by surgical method. In
cancer types diagnosed in advanced stages, chemotherapy and radiotherapy are
included in the treatment. Chemotherapy is actually called systemic therapy.
That means treatment that concerns the whole body. In systemic treatment,
besides chemotherapy, there are smart drugs and immunotherapy. Drug treatment
in cancer is determined according to the type of disease, stage, patient's age,
general condition, additional diseases, tumor character, degree of aggressiveness
of the tumor. If drug treatment is to be applied, it should be decided whether
to do this before or after surgery. While these treatment steps are on the
agenda in the early stages, drug therapy is frequently used in the advanced
stages.
With a simple blood test, the damage caused by cancer to the cell can be detected.
Cancer, which was one of the most feared diseases of the
time, is gradually moving away from being a disease to be feared with
personalized treatment. New advances in treatment continue day by day, and
cell-specific therapies that cause cancer come to the fore. In the new
generation treatment method that creates the genetic map of the cancer cell,
the inside of the cancer cell can be seen more clearly. Cancer tissue
examination or blood test is performed with this method called “Next Generation
Sequencing” NGS (Next Generation Sequencing). With the researches carried out
on the cancerous cell, the damage to be occurred on 600 roads, which prepares
the ground for the proliferation of cells, up to 600 genes, is determined and
drug treatment is applied to repair the disruption at these points.
The effect of immunotherapy is also measured
As a result of NGS examination, patients are sometimes
treated with pills and sometimes with various serum treatments. This review
also reveals how far immunotherapy can be cultivated. In the test, the
emergence of cancer at an advanced stage can give the good news that
immunotherapy will give positive results and the person can overcome the disease.
Reduces side effects of drugs
It is planned that the treatment will take place in this
direction by mapping the cancer in the NGS method, which determines which point
is damaged, which point needs repair, by mapping the cancer, which enables the
start of a new period in cancer treatment. Genetic examination of the disease
is performed with cell or blood samples taken from a patient with breast
cancer. As a result of this examination, it is determined in which way the
cancer occurs due to the disorder and how much damage the cell has caused.
Then, the drug that will repair the disorder is determined and a treatment plan
is made accordingly. Thus, the way to the patient's health is opened by using
both more effective treatment and drugs with less side effects.
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